CRM Membrane for L-Lysine Production

CRM Membrane for  L-Lysine Production
Lysine  is an α-amino acid that is used in the biosynthesis of proteins.The human body cannot synthesize lysine. It is essential in humans and must be obtained from the diet. Due to its importance in several biological processes, a lack of lysine can lead to several disease states including defective connective tissues, impaired fatty acid metabolism, anaemia, and systemic protein-energy deficiency.

Lysine is industrially produced by microbial fermentation, from a base mainly of sugar. Genetic engineering research is actively pursuing bacterial strains to improve the efficiency of production and allow lysine to be made from other substrates. Commonly, to overcome the limiting abundance of lysine in livestock feed, industrially produced lysine is added.The industrial process includes the fermentative culturing of Corynebacterium glutamicum and the subsequent purification of lysine.

L-Lysine production for animal feed is a big industry, reaching in 2018 almost 2.7 million tons  per year in China, around 70% of the global capacity. Lysine is an important additive to animal feed because it is a limiting amino acid when optimizing the growth of certain animals such as pigs and chickens for the production of meat. Lysine supplementation allows for the use of lower-cost plant protein (maize, for instance, rather than soy) while maintaining high growth rates, and limiting the pollution from nitrogen excretion. In turn, however, phosphate pollution is a major environmental cost when corn is used as feed for poultry and swine.

In China, because of the huge capacity of L-Lysine, ceramic membrane technology have seen a rapid increasing since the year 2003.  Tens of thousands of square meters ceramic membranes  filtration systems are now running for L-Lysine production in China. By using ceramic membrane, production cost and waste discharge can be greatly reduced, product yield and product quality can be greatly inhanced.  Ceramic membrane can be applied either in 98% or 65% L-Lysine.  

Process Diagram
Process Advantages
*High quality product for both 98% and 65% Lysine.
*High yield of Lysine
*Stable filtration process
*Lower producing cost
*Waste discharge greatly reduced, kindly to environment
*Extraction process simplified
*Less contamination to ion-exchange resin
*Long worklife of membrane
*Strong resistance to strong caustic and acid
*Less labor and maintenance cost
*Better operational environment.
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